Insulin resistance is associated with higher cerebrospinal fluid tau levels in asymptomatic APOE ε4 carriers

BACKGROUND: Insulin resistance (IR) is linked with the occurrence of pathological features observed in Alzheimer's disease (AD), including neurofibrillary tangles and amyloid plaques. However, the extent to which IR is associated with AD pathology in the cognitively asymptomatic stages of precl...

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Pubblicato in:J Alzheimers Dis
Autori principali: Starks, Erika J., O'Grady, J. Patrick, Hoscheidt, Siobhan M., Racine, Annie M., Carlsson, Cindy M., Zetterberg, Henrik, Blennow, Kaj, Okonkwo, Ozioma C., Puglielli, Luigi, Asthana, Sanjay, Dowling, N. Maritza, Gleason, Carey E., Anderson, Rozalyn M., Davenport-Sis, Nancy J., DeRungs, LeAnn M., Sager, Mark A., Johnson, Sterling C., Bendlin, Barbara B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583335/
https://ncbi.nlm.nih.gov/pubmed/25812851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-150072
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