Microstructural white matter alterations in preclinical Alzheimer’s disease detected using free water elimination diffusion tensor imaging

Brain changes associated with Alzheimer’s disease (AD) begin decades before disease diagnosis. While β-amyloid plaques and neurofibrillary tangles are defining features of AD, neuronal loss and synaptic pathology are closely related to the cognitive dysfunction. Brain imaging methods that are tuned...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hoy, Andrew R., Ly, Martina, Carlsson, Cynthia M., Okonkwo, Ozioma C., Zetterberg, Henrik, Blennow, Kaj, Sager, Mark A., Asthana, Sanjay, Johnson, Sterling C., Alexander, Andrew L., Bendlin, Barbara B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349685/
https://ncbi.nlm.nih.gov/pubmed/28291839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173982
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