Solubility, Antioxidation, and Oral Bioavailability Improvement of Mangiferin Microparticles Prepared Using the Supercritical Antisolvent Method

In view of the poor water solubility and low oral bioavailability of mangiferin (MG), in this study, the supercritical antisolvent (SAS) technology was used to prepare mangiferin microparticles (MG MPs) with N,N-dimethylformamide (DMF) as solvent and carbon dioxide as antisolvent, so as to improve i...

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Vydáno v:Pharmaceutics
Hlavní autoři: Liu, Mengran, Liu, Yankun, Ge, Yunlong, Zhong, Zhaoliang, Wang, Zijian, Wu, Tong, Zhao, Xiuhua, Zu, Yuangang
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076360/
https://ncbi.nlm.nih.gov/pubmed/31979138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12020090
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