Solubility, Antioxidation, and Oral Bioavailability Improvement of Mangiferin Microparticles Prepared Using the Supercritical Antisolvent Method

In view of the poor water solubility and low oral bioavailability of mangiferin (MG), in this study, the supercritical antisolvent (SAS) technology was used to prepare mangiferin microparticles (MG MPs) with N,N-dimethylformamide (DMF) as solvent and carbon dioxide as antisolvent, so as to improve i...

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Bibliographic Details
Published in:Pharmaceutics
Main Authors: Liu, Mengran, Liu, Yankun, Ge, Yunlong, Zhong, Zhaoliang, Wang, Zijian, Wu, Tong, Zhao, Xiuhua, Zu, Yuangang
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076360/
https://ncbi.nlm.nih.gov/pubmed/31979138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12020090
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