Solubility, Antioxidation, and Oral Bioavailability Improvement of Mangiferin Microparticles Prepared Using the Supercritical Antisolvent Method

In view of the poor water solubility and low oral bioavailability of mangiferin (MG), in this study, the supercritical antisolvent (SAS) technology was used to prepare mangiferin microparticles (MG MPs) with N,N-dimethylformamide (DMF) as solvent and carbon dioxide as antisolvent, so as to improve i...

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Publicat a:Pharmaceutics
Autors principals: Liu, Mengran, Liu, Yankun, Ge, Yunlong, Zhong, Zhaoliang, Wang, Zijian, Wu, Tong, Zhao, Xiuhua, Zu, Yuangang
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076360/
https://ncbi.nlm.nih.gov/pubmed/31979138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12020090
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