Solubility, Antioxidation, and Oral Bioavailability Improvement of Mangiferin Microparticles Prepared Using the Supercritical Antisolvent Method

In view of the poor water solubility and low oral bioavailability of mangiferin (MG), in this study, the supercritical antisolvent (SAS) technology was used to prepare mangiferin microparticles (MG MPs) with N,N-dimethylformamide (DMF) as solvent and carbon dioxide as antisolvent, so as to improve i...

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Publicado en:Pharmaceutics
Main Authors: Liu, Mengran, Liu, Yankun, Ge, Yunlong, Zhong, Zhaoliang, Wang, Zijian, Wu, Tong, Zhao, Xiuhua, Zu, Yuangang
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076360/
https://ncbi.nlm.nih.gov/pubmed/31979138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12020090
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