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ARL13B regulates Sonic hedgehog signaling from outside primary cilia
ARL13B is a regulatory GTPase highly enriched in cilia. Complete loss of Arl13b disrupts cilia architecture, protein trafficking and Sonic hedgehog signaling. To determine whether ARL13B is required within cilia, we knocked in a cilia-excluded variant of ARL13B (V358A) and showed it retains all know...
שמור ב:
| הוצא לאור ב: | eLife |
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| Main Authors: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
eLife Sciences Publications, Ltd
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7075693/ https://ncbi.nlm.nih.gov/pubmed/32129762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50434 |
| תגים: |
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