ExteNDing Proteome Coverage with Legumain as a Highly Specific Digestion Protease

[Image: see text] Bottom-up mass spectrometry-based proteomics utilizes proteolytic enzymes with well characterized specificities to generate peptides amenable for identification by high-throughput tandem mass spectrometry. Trypsin, which cuts specifically after the basic residues lysine and arginin...

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Foilsithe in:Anal Chem
Main Authors: Soh, Wai Tuck, Demir, Fatih, Dall, Elfriede, Perrar, Andreas, Dahms, Sven O., Kuppusamy, Maithreyan, Brandstetter, Hans, Huesgen, Pitter F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Chemical Society 2020
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7075662/
https://ncbi.nlm.nih.gov/pubmed/31951383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b03604
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