Structural and functional studies of Arabidopsis thaliana legumain beta reveal isoform specific mechanisms of activation and substrate recognition

The vacuolar cysteine protease legumain plays important functions in seed maturation and plant programmed cell death. Because of their dual protease and ligase activity, plant legumains have become of particular biotechnological interest, e.g. for the synthesis of cyclic peptides for drug design or...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Dall, Elfriede, Zauner, Florian B., Soh, Wai Tuck, Demir, Fatih, Dahms, Sven O., Cabrele, Chiara, Huesgen, Pitter F., Brandstetter, Hans
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2020
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7489914/
https://ncbi.nlm.nih.gov/pubmed/32719006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014478
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