Sirtilins – the new old members of the vitamin K‐dependent coagulation factor family

ESSENTIALS: Blood coagulation is driven by vitamin K (VK)‐dependent proteases. We have identified and characterized ‘sirtilin’ as an additional VK‐dependent protease. Sirtilins emerged early in the evolution of the coagulation system of vertebrates. Ubiquitous occurrence might indicate an important...

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Bibliographic Details
Published in:J Thromb Haemost
Main Authors: Dahms, Sven O., Demir, Fatih, Huesgen, Pitter F., Thorn, Karina, Brandstetter, Hans
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
Subjects:
COAGULATION
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850207/
https://ncbi.nlm.nih.gov/pubmed/30644641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14384
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