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Sirtilins – the new old members of the vitamin K‐dependent coagulation factor family

ESSENTIALS: Blood coagulation is driven by vitamin K (VK)‐dependent proteases. We have identified and characterized ‘sirtilin’ as an additional VK‐dependent protease. Sirtilins emerged early in the evolution of the coagulation system of vertebrates. Ubiquitous occurrence might indicate an important...

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Detalhes bibliográficos
Publicado no:J Thromb Haemost
Main Authors: Dahms, Sven O., Demir, Fatih, Huesgen, Pitter F., Thorn, Karina, Brandstetter, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850207/
https://ncbi.nlm.nih.gov/pubmed/30644641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14384
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