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Sirtilins – the new old members of the vitamin K‐dependent coagulation factor family

ESSENTIALS: Blood coagulation is driven by vitamin K (VK)‐dependent proteases. We have identified and characterized ‘sirtilin’ as an additional VK‐dependent protease. Sirtilins emerged early in the evolution of the coagulation system of vertebrates. Ubiquitous occurrence might indicate an important...

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Detalles Bibliográficos
Publicado en:J Thromb Haemost
Main Authors: Dahms, Sven O., Demir, Fatih, Huesgen, Pitter F., Thorn, Karina, Brandstetter, Hans
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850207/
https://ncbi.nlm.nih.gov/pubmed/30644641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14384
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