Comparing genome-scale DNA methylation and CNV marks between adult human cultured ITGA6+ testicular cells and seminomas to assess in vitro genomic stability

Autologous transplantation of spermatogonial stem cells is a promising new avenue to restore fertility in infertile recipients. Expansion of the initial spermatogonial stem cell pool through cell culturing is a necessary step to obtain enough cells for effective repopulation of the testis after tran...

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Pubblicato in:PLoS One
Autori principali: Struijk, Robert B., Dorssers, Lambert C. J., Henneman, Peter, Rijlaarsdam, Martin A., Venema, Andrea, Jongejan, Aldo, Mannens, Marcel M. A. M., Looijenga, Leendert H. J., Repping, Sjoerd, van Pelt, Ans M. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7075560/
https://ncbi.nlm.nih.gov/pubmed/32176716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0230253
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