Comparing genome-scale DNA methylation and CNV marks between adult human cultured ITGA6+ testicular cells and seminomas to assess in vitro genomic stability

Autologous transplantation of spermatogonial stem cells is a promising new avenue to restore fertility in infertile recipients. Expansion of the initial spermatogonial stem cell pool through cell culturing is a necessary step to obtain enough cells for effective repopulation of the testis after tran...

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Vydáno v:PLoS One
Hlavní autoři: Struijk, Robert B., Dorssers, Lambert C. J., Henneman, Peter, Rijlaarsdam, Martin A., Venema, Andrea, Jongejan, Aldo, Mannens, Marcel M. A. M., Looijenga, Leendert H. J., Repping, Sjoerd, van Pelt, Ans M. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7075560/
https://ncbi.nlm.nih.gov/pubmed/32176716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0230253
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