ITGA6+ Human Testicular Cell Populations Acquire a Mesenchymal Rather than Germ Cell Transcriptional Signature during Long-Term Culture

Autologous spermatogonial stem cell transplantation is an experimental technique aimed at restoring fertility in infertile men. Although effective in animal models, in vitro propagation of human spermatogonia prior to transplantation has proven to be difficult. A major limiting factor is endogenous...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Struijk, Robert B., Mulder, Callista L., van Daalen, Saskia K. M., de Winter-Korver, Cindy M., Jongejan, Aldo, Repping, Sjoerd, van Pelt, Ans M. M.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672582/
https://ncbi.nlm.nih.gov/pubmed/33158248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218269
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