ITGA6+ Human Testicular Cell Populations Acquire a Mesenchymal Rather than Germ Cell Transcriptional Signature during Long-Term Culture

Autologous spermatogonial stem cell transplantation is an experimental technique aimed at restoring fertility in infertile men. Although effective in animal models, in vitro propagation of human spermatogonia prior to transplantation has proven to be difficult. A major limiting factor is endogenous...

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發表在:Int J Mol Sci
Main Authors: Struijk, Robert B., Mulder, Callista L., van Daalen, Saskia K. M., de Winter-Korver, Cindy M., Jongejan, Aldo, Repping, Sjoerd, van Pelt, Ans M. M.
格式: Artigo
語言:Inglês
出版: MDPI 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672582/
https://ncbi.nlm.nih.gov/pubmed/33158248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21218269
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