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Estrogen metabolites in a small cohort of patients with idiopathic pulmonary arterial hypertension
Increased risk and severity of idiopathic pulmonary arterial hypertension (iPAH) is associated with elevated estradiol in men and postmenopausal women. Pulmonary arteries synthesise estradiol via aromatase and metabolise it via CYP1B1 to mitogenic metabolites; SNPs in aromatase and CYP1B1 have been...
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| Veröffentlicht in: | Pulm Circ |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
SAGE Publications
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7074610/ https://ncbi.nlm.nih.gov/pubmed/32206305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894020908783 |
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