Estrogen metabolites in a small cohort of patients with idiopathic pulmonary arterial hypertension

Increased risk and severity of idiopathic pulmonary arterial hypertension (iPAH) is associated with elevated estradiol in men and postmenopausal women. Pulmonary arteries synthesise estradiol via aromatase and metabolise it via CYP1B1 to mitogenic metabolites; SNPs in aromatase and CYP1B1 have been...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Pulm Circ
Päätekijät: Denver, Nina, Homer, Natalie Z.M., Andrew, Ruth, Harvey, Katie Y., Morrell, Nicholas, Austin, Eric D., MacLean, Margaret R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: SAGE Publications 2020
Aiheet:
Research Letter
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7074610/
https://ncbi.nlm.nih.gov/pubmed/32206305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894020908783
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