Estrogen metabolites in a small cohort of patients with idiopathic pulmonary arterial hypertension

Increased risk and severity of idiopathic pulmonary arterial hypertension (iPAH) is associated with elevated estradiol in men and postmenopausal women. Pulmonary arteries synthesise estradiol via aromatase and metabolise it via CYP1B1 to mitogenic metabolites; SNPs in aromatase and CYP1B1 have been...

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Dades bibliogràfiques
Publicat a:Pulm Circ
Autors principals: Denver, Nina, Homer, Natalie Z.M., Andrew, Ruth, Harvey, Katie Y., Morrell, Nicholas, Austin, Eric D., MacLean, Margaret R.
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2020
Matèries:
Research Letter
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7074610/
https://ncbi.nlm.nih.gov/pubmed/32206305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894020908783
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