Coordinated Targeting of Galanin Receptors on Cholangiocytes and Hepatic Stellate Cells Ameliorates Liver Fibrosis in Multidrug Resistance Protein 2 Knockout Mice

Galanin (Gal) is a peptide with a role in neuroendocrine regulation of the liver. In this study, we assessed the role of Gal and its receptors, Gal receptor 1 (GalR1) and Gal receptor 2 (GalR2), in cholangiocyte proliferation and liver fibrosis in multidrug resistance protein 2 knockout (Mdr2KO) mic...

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Veröffentlicht in:Am J Pathol
Hauptverfasser: Petrescu, Anca D., Grant, Stephanie, Williams, Elaina, Frampton, Gabriel, Parks, Natalie, Blaney, Hanna, Davies, Marcus, John, Rebekah, Reinhart, Evan H., McMillin, Matthew, DeMorrow, Sharon
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7074378/
https://ncbi.nlm.nih.gov/pubmed/31953035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.10.023
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