Glucocorticoids Cause Gender-Dependent Reversal of Hepatic Fibrosis in the MDR2-Knockout Mouse Model

Hepatic cholestasis is associated with a significant suppression of the hypothalamus-pituitary-adrenal axis (HPA). In the present study, we tested the hypothesis that activation of the HPA axis by corticosterone treatment can reverse liver inflammation and fibrosis in a multidrug resistance protein...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Petrescu, Anca D., Grant, Stephanie, Frampton, Gabriel, Kain, Jessica, Hadidi, Karam, Williams, Elaina, McMillin, Matthew, DeMorrow, Sharon
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5713358/
https://ncbi.nlm.nih.gov/pubmed/29125588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18112389
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