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Characterization of the phenotype with cognitive impairment and protein mislocalization in SCA34

OBJECTIVE: To better characterize the neurologic and cognitive profile of patients with spinocerebellar ataxia 34 (SCA34) caused by ELOVL4 mutations and to demonstrate the presence of ELOVL4 cellular localization and distribution abnormalities in skin-derived fibroblasts. METHODS: We investigated a...

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Bibliografiske detaljer
Udgivet i:Neurol Genet
Main Authors: Beaudin, Marie, Sellami, Leila, Martel, Christian, Touzel-Deschênes, Lydia, Houle, Gabrielle, Martineau, Laurence, Lacroix, Kevin, Lavallée, Andréane, Chrestian, Nicolas, Rouleau, Guy A., Gros-Louis, François, Laforce, Robert, Dupré, Nicolas
Format: Artigo
Sprog:Inglês
Udgivet: Wolters Kluwer 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073455/
https://ncbi.nlm.nih.gov/pubmed/32211516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000403
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