Early detection of structural abnormalities and cytoplasmic accumulation of TDP-43 in tissue-engineered skins derived from ALS patients

Amyotrophic lateral sclerosis (ALS) is an adult-onset disease characterized by the selective degeneration of motor neurons in the brain and spinal cord progressively leading to paralysis and death. Current diagnosis of ALS is based on clinical assessment of related symptoms. The clinical manifestati...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Paré, Bastien, Touzel-Deschênes, Lydia, Lamontagne, Rémy, Lamarre, Marie-Soleil, Scott, François-Dominique, Khuong, Hélène T, Dion, Patrick A, Bouchard, Jean-Pierre, Gould, Peter, Rouleau, Guy A, Dupré, Nicolas, Berthod, François, Gros-Louis, François
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359444/
https://ncbi.nlm.nih.gov/pubmed/25637145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-014-0181-z
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