Early detection of structural abnormalities and cytoplasmic accumulation of TDP-43 in tissue-engineered skins derived from ALS patients

Amyotrophic lateral sclerosis (ALS) is an adult-onset disease characterized by the selective degeneration of motor neurons in the brain and spinal cord progressively leading to paralysis and death. Current diagnosis of ALS is based on clinical assessment of related symptoms. The clinical manifestati...

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Enregistré dans:
Détails bibliographiques
Publié dans:Acta Neuropathol Commun
Auteurs principaux: Paré, Bastien, Touzel-Deschênes, Lydia, Lamontagne, Rémy, Lamarre, Marie-Soleil, Scott, François-Dominique, Khuong, Hélène T, Dion, Patrick A, Bouchard, Jean-Pierre, Gould, Peter, Rouleau, Guy A, Dupré, Nicolas, Berthod, François, Gros-Louis, François
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359444/
https://ncbi.nlm.nih.gov/pubmed/25637145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-014-0181-z
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