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Overcoming Resistance to FLT3 Inhibitors in the Treatment of FLT3-Mutated AML
Acute myeloid leukaemia (AML) carrying internal tandem duplication (ITD) of Fms-Like Tyrosine kinase 3 (FLT3) gene is associated with high risk of relapse and poor clinical outcome upon treatment with conventional chemotherapy. FLT3 inhibitors have been approved for the treatment of this AML subtype...
Gardado en:
| Publicado en: | Int J Mol Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7073218/ https://ncbi.nlm.nih.gov/pubmed/32102366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041537 |
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