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Overcoming Resistance to FLT3 Inhibitors in the Treatment of FLT3-Mutated AML

Acute myeloid leukaemia (AML) carrying internal tandem duplication (ITD) of Fms-Like Tyrosine kinase 3 (FLT3) gene is associated with high risk of relapse and poor clinical outcome upon treatment with conventional chemotherapy. FLT3 inhibitors have been approved for the treatment of this AML subtype...

詳細記述

保存先:
書誌詳細
出版年:Int J Mol Sci
主要な著者: Lam, Stephen S.Y., Leung, Anskar Y.H.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073218/
https://ncbi.nlm.nih.gov/pubmed/32102366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041537
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