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Efficient Prodrug Activator Gene Therapy by Retroviral Replicating Vectors Prolongs Survival in an Immune-Competent Intracerebral Glioma Model

Prodrug activator gene therapy mediated by murine leukemia virus (MLV)-based retroviral replicating vectors (RRV) was previously shown to be highly effective in killing glioma cells both in culture and in vivo. To avoid receptor interference and enable dual vector co-infection with MLV-RRV, we have...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Chen, Shih-Han, Sun, Jui-Ming, Chen, Bing-Mao, Lin, Sheng-Che, Chang, Hao-Fang, Collins, Sara, Chang, Deching, Wu, Shu-Fen, Lu, Yin-Che, Wang, Weijun, Chen, Thomas C., Kasahara, Noriyuki, Wang, Hsin-Ell, Tai, Chien-Kuo
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073086/
https://ncbi.nlm.nih.gov/pubmed/32093290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041433
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