Efficient Prodrug Activator Gene Therapy by Retroviral Replicating Vectors Prolongs Survival in an Immune-Competent Intracerebral Glioma Model

Prodrug activator gene therapy mediated by murine leukemia virus (MLV)-based retroviral replicating vectors (RRV) was previously shown to be highly effective in killing glioma cells both in culture and in vivo. To avoid receptor interference and enable dual vector co-infection with MLV-RRV, we have...

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Pubblicato in:Int J Mol Sci
Autori principali: Chen, Shih-Han, Sun, Jui-Ming, Chen, Bing-Mao, Lin, Sheng-Che, Chang, Hao-Fang, Collins, Sara, Chang, Deching, Wu, Shu-Fen, Lu, Yin-Che, Wang, Weijun, Chen, Thomas C., Kasahara, Noriyuki, Wang, Hsin-Ell, Tai, Chien-Kuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073086/
https://ncbi.nlm.nih.gov/pubmed/32093290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041433
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