Efficient Prodrug Activator Gene Therapy by Retroviral Replicating Vectors Prolongs Survival in an Immune-Competent Intracerebral Glioma Model

Prodrug activator gene therapy mediated by murine leukemia virus (MLV)-based retroviral replicating vectors (RRV) was previously shown to be highly effective in killing glioma cells both in culture and in vivo. To avoid receptor interference and enable dual vector co-infection with MLV-RRV, we have...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Chen, Shih-Han, Sun, Jui-Ming, Chen, Bing-Mao, Lin, Sheng-Che, Chang, Hao-Fang, Collins, Sara, Chang, Deching, Wu, Shu-Fen, Lu, Yin-Che, Wang, Weijun, Chen, Thomas C., Kasahara, Noriyuki, Wang, Hsin-Ell, Tai, Chien-Kuo
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073086/
https://ncbi.nlm.nih.gov/pubmed/32093290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041433
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