A20 Promotes Ripoptosome Formation and TNF-Induced Apoptosis via cIAPs Regulation and NIK Stabilization in Keratinocytes

The ubiquitin-editing protein A20 (TNFAIP3) is a known key player in the regulation of immune responses in many organs. Genome-wide associated studies (GWASs) have linked A20 with a number of inflammatory and autoimmune disorders, including psoriasis. Here, we identified a previously unrecognized ro...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Feoktistova, Maria, Makarov, Roman, Brenji, Sihem, Schneider, Anne T., Hooiveld, Guido J., Luedde, Tom, Leverkus, Martin, Yazdi, Amir S., Panayotova-Dimitrova, Diana
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072579/
https://ncbi.nlm.nih.gov/pubmed/32028675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020351
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