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Validation of the Spartan RXCYP2C19 Genotyping Assay Utilizing Blood Samples

The antiplatelet agent clopidogrel, a prodrug that requires bioactivation through the cytochrome P450 2C19 (CYP2C19) enzyme, is commonly prescribed post‐percutaneous coronary intervention (PCI). Genetic variation in CYP2C19 contributes to individual variability in clopidogrel response, and can lead...

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Dades bibliogràfiques
Publicat a:Clin Transl Sci
Autors principals: Davis, Brittney H., DeFrank, Gina, Limdi, Nita A., Harada, Shuko
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070822/
https://ncbi.nlm.nih.gov/pubmed/31664775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12714
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