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Practical Consideration of Genotype Imputation: Sample Size, Window Size, Reference Choice, and Untyped Rate

Imputation offers a promising way to infer the missing and/or untyped genotypes in genetic studies. In practice, however, many factors may affect the quality of imputation. In this study, we evaluated the influence of untyped rate, sizes of the study sample and the reference sample, window size, and...

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Bibliografske podrobnosti
Main Authors: Zhang, Boshao, Zhi, Degui, Zhang, Kui, Gao, Guimin, Limdi, Nita N., Liu, Nianjun
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269888/
https://ncbi.nlm.nih.gov/pubmed/22308193
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