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Validation of a Ligand Binding Assay Using Dried Blood Spot Sampling

Dried blood spots (DBS) technology has been introduced as a microsampling alternative to traditional plasma or serum sampling for pharmacokinetics or toxicokinetics evaluation. The application of DBS has been established for many small molecule drugs at discovery, nonclinical, and clinical stages. H...

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Bibliographic Details
Main Authors: Burns, Daniel, Brunner, Laura, Rajendran, Surendran, Johnson, Beth, Ma, Mark, Wang, Jin
Format: Artigo
Language:Inglês
Published: Springer US 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535112/
https://ncbi.nlm.nih.gov/pubmed/23135927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9430-x
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