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Validation of a Ligand Binding Assay Using Dried Blood Spot Sampling

Dried blood spots (DBS) technology has been introduced as a microsampling alternative to traditional plasma or serum sampling for pharmacokinetics or toxicokinetics evaluation. The application of DBS has been established for many small molecule drugs at discovery, nonclinical, and clinical stages. H...

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Detalhes bibliográficos
Main Authors: Burns, Daniel, Brunner, Laura, Rajendran, Surendran, Johnson, Beth, Ma, Mark, Wang, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535112/
https://ncbi.nlm.nih.gov/pubmed/23135927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9430-x
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