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Validation of the Spartan RXCYP2C19 Genotyping Assay Utilizing Blood Samples

The antiplatelet agent clopidogrel, a prodrug that requires bioactivation through the cytochrome P450 2C19 (CYP2C19) enzyme, is commonly prescribed post‐percutaneous coronary intervention (PCI). Genetic variation in CYP2C19 contributes to individual variability in clopidogrel response, and can lead...

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Detalles Bibliográficos
Publicado en:Clin Transl Sci
Main Authors: Davis, Brittney H., DeFrank, Gina, Limdi, Nita A., Harada, Shuko
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070822/
https://ncbi.nlm.nih.gov/pubmed/31664775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12714
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