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Engineering of an enhanced synthetic Notch receptor by reducing ligand-independent activation
Notch signaling is highly conserved in most animals and plays critical roles during neurogenesis as well as embryonic development. Synthetic Notch-based systems, modeled from Notch receptors, have been developed to sense and respond to a specific extracellular signal. Recent advancement of synNotch...
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| Publicado no: | Commun Biol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7069970/ https://ncbi.nlm.nih.gov/pubmed/32170210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0848-x |
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