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Cis-interactions between Notch and its ligands block ligand-independent Notch activity
The Notch pathway is integrated into numerous developmental processes and therefore is fine-tuned on many levels, including receptor production, endocytosis, and degradation. Notch is further characterized by a twofold relationship with its Delta-Serrate (DSL) ligands, as ligands from opposing cells...
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| Publicado no: | eLife |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4286723/ https://ncbi.nlm.nih.gov/pubmed/25486593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04415 |
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