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Cis-interactions between Notch and its ligands block ligand-independent Notch activity

The Notch pathway is integrated into numerous developmental processes and therefore is fine-tuned on many levels, including receptor production, endocytosis, and degradation. Notch is further characterized by a twofold relationship with its Delta-Serrate (DSL) ligands, as ligands from opposing cells...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:eLife
Κύριοι συγγραφείς: Palmer, William Hunt, Jia, Dongyu, Deng, Wu-Min
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: eLife Sciences Publications, Ltd 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286723/
https://ncbi.nlm.nih.gov/pubmed/25486593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04415
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