A carregar...
Synthesis of montbretin A analogues yields potent competitive inhibitors of human pancreatic α-amylase
Simplified analogues of the potent human amylase inhibitor montbretin A were synthesised and shown to bind tightly, K(I) = 60 and 70 nM, with improved specificity over medically relevant glycosidases, making them promising candidates for controlling blood glucose. Crystallographic analysis confirmed...
Na minha lista:
| Publicado no: | Chem Sci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2019
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7069248/ https://ncbi.nlm.nih.gov/pubmed/32206255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc02610j |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|