Potent Human α-Amylase Inhibition by the β-Defensin-like Protein Helianthamide

[Image: see text] Selective inhibitors of human pancreatic α-amylase (HPA) are an effective means of controlling blood sugar levels in the management of diabetes. A high-throughput screen of marine natural product extracts led to the identification of a potent (K(i) = 10 pM) peptidic HPA inhibitor,...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:ACS Cent Sci
Hoofdauteurs: Tysoe, Christina, Williams, Leslie K., Keyzers, Robert, Nguyen, Nham T., Tarling, Chris, Wicki, Jacqueline, Goddard-Borger, Ethan D., Aguda, Adeleke H., Perry, Suzanne, Foster, Leonard J., Andersen, Raymond J., Brayer, Gary D., Withers, Stephen G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2016
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819454/
https://ncbi.nlm.nih.gov/pubmed/27066537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.5b00399
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items