Novel Peptide-Based PD1 Immunomodulators Demonstrate Efficacy in Infectious Disease Vaccines and Therapeutics

Many pathogens use the same immune evasion mechanisms as cancer cells. Patients with chronic infections have elevated levels of checkpoint receptors (e.g., programed cell death 1, PD1) on T cells. Monoclonal antibody (mAb)-based inhibitors to checkpoint receptors have also been shown to enhance T-ce...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Kotraiah, Vinayaka, Phares, Timothy W., Browne, Cecille D., Pannucci, James, Mansour, Marc, Noe, Amy R., Tucker, Kenneth D., Christen, Jayne M., Reed, Charles, MacKay, Alecia, Weir, Genevieve M., Rajagopalan, Rajkannan, Stanford, Marianne M., Chung, Chun-Shiang, Ayala, Alfred, Huang, Jing, Tsuji, Moriya, Gutierrez, Gabriel M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7068811/
https://ncbi.nlm.nih.gov/pubmed/32210956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00264
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge