A Peptide-Based PD1 Antagonist Enhances T-Cell Priming and Efficacy of a Prophylactic Malaria Vaccine and Promotes Survival in a Lethal Malaria Model

The blockade of programmed cell death-1 (PD1) and its ligand PDL1 has been proven to be a successful immunotherapy against several cancers. Similar to cancer, PD1 contributes to the establishment of several chronic infectious diseases, including malaria. While monoclonal antibodies (mAbs) targeting...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Phares, Timothy W., Kotraiah, Vinayaka, Karunarathne, Deshapriya S., Huang, Jing, Browne, Cecille D., Buontempo, Peter, Mansour, Marc, Noe, Amy R., Wykes, Michelle N., Pannucci, James, Tsuji, Moriya, Gutierrez, Gabriel M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363839/
https://ncbi.nlm.nih.gov/pubmed/32733457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01377
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados