NK Cells Augment Oncolytic Adenovirus Cytotoxicity in Ovarian Cancer

Oncolytic viruses (OVs) can trigger profound innate and adaptive immune responses, which have the potential both to potentiate and reduce the activity of OVs. Natural killer (NK) cells can mediate potent anti-viral and anti-tumoral responses, but there are no data on the role of NK cells in oncolyti...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Leung, Elaine Y.L., Ennis, Darren P., Kennedy, Philippa R., Hansell, Christopher, Dowson, Suzanne, Farquharson, Malcolm, Spiliopoulou, Pavlina, Nautiyal, Jaya, McNamara, Sophie, Carlin, Leo M., Fisher, Kerry, Davis, Daniel M., Graham, Gerard, McNeish, Iain A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7068056/
https://ncbi.nlm.nih.gov/pubmed/32195317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2020.02.001
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