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A high ATP concentration enhances the cooperative translocation of the SARS coronavirus helicase nsP13 in the unwinding of duplex RNA

Severe acute respiratory syndrome coronavirus nonstructural protein 13 (SCV nsP13), a superfamily 1 helicase, plays a central role in viral RNA replication through the unwinding of duplex RNA and DNA with a 5′ single-stranded tail in a 5′ to 3′ direction. Despite its putative role in viral RNA repli...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Jang, Kyoung-Jin, Jeong, Seonghwan, Kang, Dong Young, Sp, Nipin, Yang, Young Mok, Kim, Dong-Eun
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066239/
https://ncbi.nlm.nih.gov/pubmed/32161317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61432-1
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