Phosphofructokinase 1 Platelet Isoform Promotes β-Catenin Transactivation for Tumor Development

Metabolism plays a critical role in direct regulation of a variety of cellular activities via metabolic enzymes and metabolites. Here, we demonstrate that phosphofructokinase 1 platelet isoform (PFKP), which catalyzes a rate-limiting reaction in glycolysis, promotes EGFR activation-induced nuclear t...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Lee, Jong-Ho, Shao, Fei, Ling, Jinjie, Lu, Sean, Liu, Rui, Du, Linyong, Chung, Jin Woong, Koh, Sang Seok, Leem, Sun-Hee, Shao, Jichun, Xing, Dongming, An, Zhiqiang, Lu, Zhimin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7066116/
https://ncbi.nlm.nih.gov/pubmed/32195176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00211
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