EGFR-Phosphorylated Platelet Isoform of Phosphofructokinase 1 Promotes PI3K Activation

EGFR activates phosphatidylinositide 3-kinase (PI3K), but the mechanism underlying this activation is not completely understood. We demonstrated here that EGFR activation resulted in lysine acetyltransferase 5 (KAT5)-mediated K395 acetylation of the platelet isoform of phosphofructokinase 1 (PFKP) a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Lee, Jong-Ho, Liu, Rui, Li, Jing, Wang, Yugang, Tan, Lin, Li, Xin-Jian, Qian, Xu, Zhang, Chuanbao, Xia, Yan, Xu, Daqian, Guo, Wei, Ding, Zhiyong, Du, Linyong, Zheng, Yanhua, Chen, Qianming, Lorenzi, Philip L., Mills, Gordon B, Jiang, Tao, Lu, Zhimin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6114939/
https://ncbi.nlm.nih.gov/pubmed/29677490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.03.018
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados