Diverse effects of interferon alpha on the establishment and reversal of HIV latency

HIV latency is the major barrier to a cure for people living with HIV (PLWH) on antiretroviral therapy (ART) because the virus persists in long-lived non-proliferating and proliferating latently infected CD4(+) T cells. Latently infected CD4(+) T cells do not express viral proteins and are therefore...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Van der Sluis, Renée M., Zerbato, Jennifer M., Rhodes, Jake W., Pascoe, Rachel D., Solomon, Ajantha, Kumar, Nitasha A., Dantanarayana, Ashanti I., Tennakoon, Surekha, Dufloo, Jérémy, McMahon, James, Chang, Judy J., Evans, Vanessa A., Hertzog, Paul J., Jakobsen, Martin R., Harman, Andrew N., Lewin, Sharon R., Cameron, Paul U.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7065813/
https://ncbi.nlm.nih.gov/pubmed/32109259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008151
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