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PD-1 contributes to the establishment and maintenance of HIV-1 latency
OBJECTIVE: In HIV-infected individuals on antiretroviral therapy (ART), latent HIV is enriched in CD4(+) T-cells expressing immune checkpoint molecules (ICs), in particular programmed cell death-1 (PD-1). We therefore assessed the effect of blocking PD-1 on latency, both in vitro and in vivo. METHOD...
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| Publicado no: | AIDS |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6026054/ https://ncbi.nlm.nih.gov/pubmed/29746296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001849 |
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