PD-1 is a marker for abnormal distribution of naïve/memory T cell subsets in HIV-1 infection

Chronic activation of T cells is a hallmark of HIV-1 infection and plays an important role in disease progression. We previously showed that the engagement of the inhibitory receptor PD-1 on HIV-1 specific CD4(+) and CD8(+) T cells leads to their functional exhaustion in vitro. However, little is kn...

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Détails bibliographiques
Auteurs principaux: Breton, Gaëlle, Chomont, Nicolas, Takata, Hiroshi, Fromentin, Rémi, Ahlers, Jeffrey, Filali-Mouhim, Abdelali, Riou, Catherine, Boulassel, Mohamed-Rachid, Routy, Jean-Pierre, Yassine-Diab, Bader, Sékaly, Rafick-Pierre
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815464/
https://ncbi.nlm.nih.gov/pubmed/23918986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200646
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