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PD-1 is a marker for abnormal distribution of naïve/memory T cell subsets in HIV-1 infection
Chronic activation of T cells is a hallmark of HIV-1 infection and plays an important role in disease progression. We previously showed that the engagement of the inhibitory receptor PD-1 on HIV-1 specific CD4(+) and CD8(+) T cells leads to their functional exhaustion in vitro. However, little is kn...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3815464/ https://ncbi.nlm.nih.gov/pubmed/23918986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200646 |
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