Autologous HIV-1 Clade-B Nef Peptides Elicit Increased Frequency, Breadth and Function of CD8(+) T-Cells Compared to Consensus Peptides

OBJECTIVE: To determine the function and phenotype of CD8(+) T-cells targeting consensus and autologous sequences of entire HIV-1 Nef protein. METHODS: Multiparameter flow cytometry-based analysis was used to evaluate the responses of two treatment naïve HIV-infected individuals, during primary and...

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Main Authors: Doroudchi, Mehrnoosh, Yegorov, Oleg, Baumgartner, Tom, Kernaleguen, Anne-Elen, Breton, Gaelle, Ndongala, Michel L., Boulassel, Mohamed-Rachid, Routy, Jean-Pierre, Bernard, Nicole F., Sékaly, Rafick-Pierre, Yassine-Diab, Bader
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501503/
https://ncbi.nlm.nih.gov/pubmed/23185362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049562
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