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Combination immune checkpoint blockade to reverse HIV latency

In people living with HIV (PLWH) on antiretroviral therapy (ART), HIV latency is the major barrier to a cure. HIV persists preferentially in CD4(+) T cells expressing multiple immune checkpoint (IC) molecules, including programmed death (PD)-1, T cell immunoglobulin and mucin-domain containing-3 (TI...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Van der Sluis, Renée M., Kumar, Nitasha A., Pascoe, Rachel D., Zerbato, Jennifer M., Evans, Vanessa A., Dantanarayana, Ashanti I., Anderson, Jenny L., Sékaly, Rafick P., Fromentin, Rémi, Chomont, Nicolas, Cameron, Paul U., Lewin, Sharon R.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354848/
https://ncbi.nlm.nih.gov/pubmed/31988180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901191
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